Cover Image
close this bookProtein-Energy Requirements of Developing Countries: Evaluation of New Data (UNU, 1981, 268 p.)
close this folderNitrogen absorption-adults
close this folderProtein absorption of adult men with intestinal helminthic parasites
View the document(introduction...)
View the documentObjective
View the documentExperimental details
View the documentSummary of the main results
View the documentConclusions and comments

Conclusions and comments

  1. The men had light intestinal loads of helminths.
  2. Apparent protein digestibility improved after treatment in some but not all men. Energy absorption was not affected by the parasites.
  3. Nitrogen balance was not affected by the parasites.
  4. Unusually heavy infestations with an intestinal helminth can probably interfere with the intake, absorption, and retention of proteins, but the mere presence of a parasite does not justify an assumption of metabolic or clinical significance. The contribution of these parasites to protein malnutrition is often overemphasized.

TABLE 4. Nitrogen-Balance Data

Nitrogen

Group A
Ascaris
(n = 7)

Group B
Ascaris+ hookworm
(n = 6)

Group C
Hookworm
(n = 7)

Intake (mg N/kg/day)  
Before deworming

204.9 11.1

241.1 9.3

2218. 11.3

After deworming

209.7 13.8

245.6 8.1

226.9 6.8

Urinary nitrogen output (mg N/kg/day)  
Before

135.8 6.3

147.4

123.6 7.6

After

136.3 7.0

163.1 5.9*

142.7 9.0

Faecal nitrogen output(mg N/kg/day)  
Before

44.1 4.3

58.1 3.3

53.1 4.4

After

42.6 4.3

53.6 4.4

43.5 4.1

Nitrogen Balance(mg N/kg/day)  
Before

20.0 4.3

30.6 10.0

40.7 6.5

After

25.9 7.4

24.1 9.1

35.6 9.2

True digestibility (%)      
Before

84.6 1.0

81.0 0.8

81.7 1.4

After

86.0 1.4

83.2 1.4

86.2 1.7

Biological value (%)  
Before

36.3 1.7

34.8 3.2

43.0 3.3

After

38.2 2.5

31.6 3.0

39.5 3.9

NPU (%)  
Before

30.7 1.6

28.1 2.1

35.4 3.3

After

32.8 2.3

26.3 2.7

34.1 3.5

Changes with deworming: * p < 0.05; ** p < 0.01.

TABLE 5. Haematological Observations

Group

Parasite

Subject no.

Haemoglobin

Haematocrit

Initial

Final

Difference

Initial

Final

Difference

A

Ascaris

Lumbricoides

4

14.5

15.5

1.0

41

45

4

6

14.0

15.4

1.4

40

45

5

8

14.2

14.8

0.6

40

42

2

10

13.8

13.7

- 0.1

41

41

0

12

13.7

13.7

0

41

40

- 1

22

14.5

14.2

- 0 3

45

40

5

31

14.8

15.0

0.2

43

43

0

B

Ascaris +

hookworm

3

13.3

14.9

1.6

37

43

6

7

14.5

15.7

1.2

41

45

4

9

14.4

15.4

1.0

46

41

- 5

21

15.0

15.6

0.6

43

45

3

28

14.2

14.7

0.5

41

41

0

30

14.6

15.3

0.7

43

44

1

C

Hookworm

1

16.1

17.1

1.0

48

50

2

3

11.5

12.0

0.5

33

36

3

11

14.0

14.6

0.6

41

43

2

23

14.4

16.2

1.8

43

46

3

24

13.8

14.0

0.2

40

41

1

25

13.6

14.4

0.8

39

42

3

29

14.0

14.6

0.6

41

42

1